Study of calcium regulating hormones in calcium stone formers

The present study demonstrated that calcium stone formers possesses significant decrease in 1.25 [OH]2 Vit D; 24, 25 [OH]2 Vit D and Vit. D binding protein as compared to control. This finding is accompanied with high activity of alkaline phosphatase due to bone fraction elevation, and serum hypocalcaemia as well as hypophosphataemia. The interesting finding was the inactivation of superoxide dismutase [SOD] couple with hypercalciuria, and elevation of urine citric acid content

Role of heme and its indication to Hb affinity with relevant to probiotic

The aim of this work was to reveal the role of fermented soy been as a type of feeding and is role in enhancement of the probiotic growth. Study was conducted on 27 mice of two months age and 100g average weight. Animals were divided into three groups, control group, animals receiving fermented soy bean as a major food and the third one on non-fermented soy bean. Animals that received fermented soy bean showed an enhancement in the oxyhemoglobin concentration that was concomitant with non elevation of the non-functional hemoglobin derivatives. Results obtained from the absorption spectra of hemoglobin also showed some indication of increasing the molecule stability that revealed by the height and width the peat at 280nm that characteristic to the abnormal motion of the hemoglobin molecule. Electrical conductivity measurements recorded a significant decrease indicating more stability of hemoglobin. An appreciable increase in hemoglobin enthalpy and entropy were detected in group III that received fermented soy bean. An opposite behavior was recorded regarding the free energy

Hemoglobin structure in thalassemia and the effect of splenoctomy

This study was conducted to 81 patients suffering from thalassemia, the aim of the work was to evaluate the role of the properties of the heme atom in the hemoglobin molecule and to what extend thalassemia may alter the normal magnetic behavior of it. Patients were divided into 2 groups: heterozygous, homozygous which was subdivided into two subgroups [splenoctomic and non-splenoctomic patients] and the normal control group. Results showed that the blood count of these patients was almost near to the normal in the heterozygous, non-splenoctomic patients showed higher levels of non-functional hemoglobin derivatives. Magnetic properties of heme as measured in magnetic susceptibility, auto-oxidation rate and also results obtained from the absorption spectra of hemoglobin verify that heme atom in both homozygous groups were elevated, Non-splenoctomic patients showed the highest level hence its heme atoms shifted to the paramagnetic region in which heme cannot carry out its normal function and has a low affinity of both oxygen and globin